Biomedical literature search
Research demo, not for clinical use: results must not inform medical decisions.
Each example shows the five abstracts that MedCPT ranks highest for the query, precomputed with the biomed-search command. Queries are embedded with MedCPT’s query encoder and abstracts with its article encoder, both running in JAX with eqx-zoo and verified against Hugging Face Transformers.
The corpus is small: 10,000 openly licensed abstracts from two weeks of publications. Some questions have no directly relevant article in it, and the search still returns its closest matches. It includes animal and laboratory research. Preprints, which have not been peer-reviewed, are labelled.
Retrieval quality, the method and the limitations are described in the repository, which also explains how to search with your own queries. The corpus and its embeddings are published as a dataset.
“sleep problems in older adults”
- Older injured adults reported sleep disturbances: a cross-sectional study.
BACKGROUND: Sleep disturbances are common among older adults recovering from traumatic injury and are associated with delayed psychological and functional recovery. Despite their prevalence, few studies have examined sleep disturbances early after injury in this population. This study evaluated the prevalence of …
- The effects of Qigong exercise on sleep quality in older adults: a systematic review and meta-analysis.
BACKGROUND: Sleep disturbances are common among older adults. While pharmacological treatments may offer short-term relief, they are often associated with adverse effects. Non-pharmacological interventions are thus urgently needed. Qigong, a traditional Chinese practice known for its safety and adaptability, has …
- A Randomized, Triple-Blind, Placebo-Controlled, Parallel Clinical Trial Investigating Safety and Efficacy of Corn Leaf Extract on Sleep Quality in a Healthy Population With Difficulty Falling or Staying Asleep.
Difficulties falling and/or staying asleep affect over one quarter of adults in the United States. Current management strategies include prescription sleep aids. However, long-term use is associated with serious adverse effects. Therefore, natural alternative sleep aids that may provide safer and more effective …
- Better sleep is associated with improved mobility in adults: a scoping review.
OBJECTIVE: To review the literature on whether sleep impacts mobility in adults. METHODS: Ovid Medline, Web of Science, Embase, and CINAHL databases were searched. Citations were randomly divided so that each was screened separately by 2 authors. Data were extracted from included articles independently by 2 …
- Persistent sleep symptoms in post-COVID syndrome: a Brazilian prospective clinical study.
Post coronavirus disease (COVID) syndrome is a frequent condition, resulting from the persistence of symptoms or the development of new ones, after 12 weeks of acute severe acute respiratory syndrome coronavirus 2 infection. The impact on sleep was observed worldwide, whether in the acute phase due to the direct …
“antibiotic resistance in hospital patients”
- Molecular Characterization of Carbapenem and Colistin Resistance in Isolates Causing Urinary Tract Infections at an Outpatient Setting of a Tertiary Care Hospital.
Background Increasing resistance to higher-end antibiotics like carbapenems and colistin is a great cause of concern. There is a paucity of data on the detection of carbapenem and colistin in outpatient settings. This study was to determine the prevalence of carbapenem-resistant Enterobacterales (CRE) and colistin …
- Clinical Epidemiological Analysis of the Genotypic Spectrum and Mortality Risk in Carbapenem-Resistant Klebsiella pneumoniae (CRKP) Infections.
BACKGROUND: Carbapenem-resistant Klebsiella pneumoniae (CRKP) has become a global public health threat, with significantly increased morbidity and mortality among high-risk inpatients. High-risk genotypes of CRKP, primarily including K. pneumoniae carbapenemase (KPC), oxacillinase-48-like (OXA-48-like), New Delhi …
- Improving antibiotic prescribing in LMICs: Insights from an outpatient clinic in Pakistan.
BACKGROUND: Most human antibiotic use occurs in outpatient care and is a key driver of antimicrobial resistance (AMR). Although sales statistics suggest that high-income countries consume more antibiotics overall, the steepest growth is seen in low- and middle-income countries. Sales data - incomplete and non- …
- Antibiotic Prescribing in Patients Presenting with COVID-19: A Closed-Loop Audit with a Targeted Educational Intervention in a South Australian Hospital.
Background/Objectives: Antimicrobial resistance is an escalating public health threat. Despite the low prevalence of community-acquired bacterial coinfection (CABC) in patients presenting with COVID-19, antibiotics are frequently prescribed. We evaluated antibiotic prescribing for suspected CABC in adults admitted …
- Discharge Delays and Costs Associated With Outpatient Parenteral Antimicrobial Therapy for Multidrug-Resistant Organisms: A Retrospective Cohort Study.
BACKGROUND: Outpatient parenteral antimicrobial therapy (OPAT) coordination is challenging in multidrug-resistant organism (MDRO)-infected patients. The study purpose was to describe barriers and medication costs associated with OPAT utilizing therapies for MDRO. METHODS: This was an institutional review board- …
“statins and breast cancer survival”
- Statin-dye conjugates for selective targeting of KRAS mutant cancer cells.
Over 90% of pancreatic ductal adenocarcinoma (PDAC) patients involve KRAS mutations (KRASMUT), for which current treatment options are limited. Statins, commonly used to lower cholesterol, have demonstrated certain selective toxicity towards KRAS-transformed cells, prompting the question of whether statin-based …
- Multi-Omics Integration Identifies the Cholesterol Metabolic Enzyme DHCR24 as a Key Driver in Breast Cancer.
Dysregulated cholesterol metabolism is a hallmark of breast cancer (BC), but its key molecular mediators remain unclear. Using an integrated multi-omics approach, including Mendelian randomization, transcriptomic/proteomic database screening, functional assays, and clinical correlation, we identified the cholesterol …
- Breast Cancer: Molecular Pathogenesis, Targeted Therapy, Screening, and Prevention.
Breast cancer is the most common cancer and the leading cause of cancer-related death among women worldwide. Advances in molecular biology, high-throughput sequencing, and integrative-omics have deepened the understanding of its heterogeneity by clarifying mechanisms linked to genetic susceptibility, epigenetic …
- RISE UP for breast cancer 2024: conference highlights & takeaways.
RISE UP (Revolutionizing Investigations to StEp Up Prevention) for breast cancer brought together leading cancer specialists, women's health providers, basic and population scientists, regulators, politicians, industry leaders, patient advocates, and more from around the world to discuss and chart a radical …
- Research progress in the prevention and treatment of radiation-induced heart disease.
Radiotherapy (RT) is a cornerstone treatment for thoracic malignancies, but is associated with an increased risk of radiation-induced heart disease (RIHD), a major cause of long-term morbidity and mortality in cancer survivors. Ionizing radiation directly damages cellular components (proteins, lipids, and DNA), …
“exercise and depression”
- The longitudinal relations between physical activity, inflammation, and depression in the Health and Retirement Study.
Physical activity appears associated with lower depression in treatment and epidemiological studies but specific biological mechanisms remain unclear. Research supports inflammation being positively associated with depression and negatively associated with physical activity, suggesting it could mediate physical …
- The role of depression in the progression of tumor cell inflammation and the potential regulatory mechanisms of aerobic exercise: a narrative review from molecular and cellular perspectives.
There is a tight correlation between depression, and tumor progression, particularly via the regulation of the immune system, and inflammatory responses. Chronic inflammation is a member of the core causes in the tumor microenvironment, which can promote tumor initiation, progression, and immune evasion. An …
- Seasonality in mood disorders: Probing association of accelerometer-derived physical activity with daylength and solar insolation.
Mood disorders are the leading cause of disability worldwide. Up to 30 percent of individuals with major depressive disorder (MDD) and bipolar disorder (BD) display a seasonal pattern of onset, a phenomenon now recognized in the official diagnostic manuals (DSM-5 and ICD-11). Very little is known about the influence …
- Associations of Domain-Specific Physical Activity With Mental Health Symptoms Among Finnish Employed Adults: A Population-Based Study.
Leisure-time physical activity has consistently been associated with better mental health. However, evidence on active commuting and occupational physical activity is less conclusive. We examined cross-sectional associations of domain-specific physical activity with depressive symptoms and psychological distress …
- Prevalence of mental health in relation to religious practices in a contemporary small-scale older Amdo Tibetans.
Amdo Tibetans, a devout and cohesive non-industrial society, intertwine religious practices, such as pray, kowtow, and pilgrimage, aspect of their private and public lives. This unique cultural and religious framework fosters a profound connection between their religious practices and health behaviors. The primary …
“air pollution and asthma in children”
- Can a single pollen measurement site provide exposure information for health research across an entire state? Results from a study of allergic-type asthma associated with thunderstorms (2007-2018).
BACKGROUND: Thunderstorm asthma is an increase in severe asthma following thunderstorm events during high pollen conditions. However, sparse pollen measurements hinder epidemiological research of this phenomenon. OBJECTIVE: Is pollen measured at a single site predictive of thunderstorm asthma risk across a broad …
- Effect of ambient particulate matter pollution on disease burden globally: a systematic analysis of the global burden of disease study 2021.
BACKGROUND: Particulate matter (PM) refers to solid or liquid particles suspended in the atmosphere. These particles can be inhaled during normal respiration, leading to various respiratory diseases including upper respiratory tract infections (URTIs). We comprehensively evaluated the ambient particulate matter …
- The association between air pollution exposure and childhood cancer: a scoping review about the challenges in epidemiological studies.
BACKGROUND AND OBJECTIVE: Although several studies have investigated the association between various air pollutants and the risk of childhood cancer, particularly leukemia, results are still inconclusive. This scoping review aims to identify and discuss the main methodological challenges observed in publications …
- Interactive Effects of Genetic Susceptibility and Early-Life Tobacco Smoke Exposure on the Asthma-Eczema Complex Phenotype in Children: 6-Year Follow-Up Case-Control Study.
Atopic eczema and asthma frequently co-occur, forming a distinct complex phenotype that likely arises from shared genetic pathways and early-life environmental influences. We aimed to investigate whether variants in TNS1 and NRXN1-previously identified in a genome-wide interaction study-influence susceptibility to …
- Impact of improved stove intervention on infant acute respiratory infections: Results from a randomized trial in Northwest Ethiopia.
BACKGROUND: Globally, millions of young children affected by acute respiratory infections every year, which is the leading cause of death and serious illness among children. Though strategies, including promoting improved stoves, have been implemented to combat this public health challenge, the effectiveness of local …
“gut microbiome and obesity”
- Targeting gut microbiota with short-chain fructo-oligosaccharides prebiotic fibers to support metabolic health in overweight prediabetic adults: a randomized, double-blinded, placebo-controlled study.
BACKGROUND AND OBJECTIVES: The global rise in metabolic disorders such as obesity and type 2 diabetes is largely driven by dietary changes and sedentary lifestyles. Prebiotic dietary fibers may help mitigate this trend by modulating gut microbiota. This study aimed to evaluate the effects of short-chain fructo- …
- The gut microbiota-obesity axis in the pathogenesis and prognosis of breast cancer.
BACKGROUND: Breast cancer (BC) remains a major global health concern, accounting for 11.7% of all cancer cases and ranking as the second leading cause of female cancer-related deaths worldwide. Increasing evidence highlights the interplay between gut microbiota (GM) dysbiosis and obesity-associated metabolic …
- Microbiota-Mediated Bile Acid Metabolism as a Mechanistic Framework for Precision Nutrition in Gastrointestinal and Metabolic Diseases.
Gut microbiota play a central role in shaping bile acid (BA) metabolism through community-specific capacities for deconjugation, dehydroxylation, and other transformation reactions. Distinct microbiome compositional patterns-often referred to as enterotype-like clusters-correspond to reproducible functional profiles …
- High maternal body condition score in beef cattle: gut microbiota dysbiosis, immune dysregulation and offspring health implications.
INTRODUCTION: This study investigates the correlation between intestinal flora and body condition score (BCS) in beef cattle, focusing on the impact of maternal body condition on gut microbiota and immune function in both cows and their offspring. MATERIAL AND METHODS: Faecal and blood samples were collected at …
- Prominent mediatory role of gut microbiome in the effect of lifestyle on host metabolic phenotypes.
Lifestyle factors influence both gut microbiome composition and host metabolism, yet their combined and mediating effects on host phenotypes remain poorly characterized in cardiometabolic populations. In 1,643 participants from the MetaCardis study, we developed a composite lifestyle score (QASD: dietary quality, …
“long-term effects of COVID-19”
- Long-Term Self-Reported Symptoms Among Adults After COVID-19 Infection in the West Bank: A Cross-Sectional Analysis.
INTRODUCTION: With growing recognition of the prolonged effects of COVID-19, there is an urgent need to understand its extended clinical and public health implications across diverse settings. Long-term consequences following SARS-CoV-2 infection remain insufficiently studied in Middle Eastern populations. This study …
- Elevated Risk of an Emergency Department Admission Associated With Long COVID Diagnosis Within the US Veteran Population.
Long COVID has emerged as a significant public health concern, potentially affecting millions of people over the next decade. By examining the risk of an emergency department (ED) visit associated with long COVID across a population, we can see the population-level severity of long COVID. This study aims to quantify …
- Prevalence and associated factors with long COVID in the Brazilian population: The role of health-related behaviors and sociodemographic characteristics.
The disease caused by the 2019 coronavirus (COVID-19) has resulted in unprecedented morbidity and mortality worldwide, with many individuals experiencing persistent symptoms and a decline in quality of life after infection. This study aims to analyze the prevalence and associated factors of long COVID in the …
- Change in healthcare utilization before and after COVID-19 using data from 1.5 million individuals.
BACKGROUND AND OBJECTIVE: Post-infectious sequelae can increase burden on healthcare systems. We aimed to assess the long-term effect of COVID-19 on healthcare utilization across all levels of care. METHODS: In this register-based cohort study, we included all adult (≥18 years) residents in Sweden's two largest …
- Impact of the COVID-19 pandemic on long-term trends in youth depression and anxiety.
Adolescent depression and anxiety have been rising in recent decades. Although reviews point at deterioration of youth mental health during the COVID-19 pandemic, how this relates to pre-pandemic trends is unclear. This narrative review examines whether the COVID-19 pandemic has impacted the long-term development of …
“screening for diabetic retinopathy with deep learning”
- Automated retinal disease classification using deep learning and AlexNet with statistical models analysis.
Diabetic Retinopathy, Cataract, and Glaucoma are major retinal diseases that require early detection to prevent irreversible vision loss. This study proposes a deep learning-based framework for the automated classification of retinal images into four categories: Normal, Diabetic Retinopathy, Cataract, and Glaucoma. …
- FKG-MM: A multi-modal fuzzy knowledge graph with data integration in healthcare.
Artificial Intelligence (AI) has been dramatically applied to healthcare in various tasks to support clinicians in disease diagnosis and prognosis. It has been known that accurate diagnosis must be drawn from multiple evidence, namely clinical records, X-Ray images, IoT data, etc called the multi-modal data. Despite …
- Assessment of Blood Glucose Measurement Using New Noninvasive Technology: Protocol and Methodology.
BACKGROUND: Diabetes mellitus (DM) is a major noncommunicable disease with a significant increase in prevalence, especially in low- and middle-income countries. The latest International Diabetes Federation Diabetes Atlas (2025) reports that 11.1% of the adult population (20 to 79 years old) is living with diabetes, …
- An improved tortuosity measurement method combining curvature-based, breadth-first search and Euclidean distance for retinal image analysis.
Retinal vascular tortuosity is a clinically relevant biomarker linked to systemic and ocular diseases; however, its quantitative assessment particularly the distinction between arteries and veins remains underexplored in both healthy and pathological conditions. This study investigates tortuosity behavior using three …
- Low-Cost and Fast Epiretinal Membrane Detection and Quantification Based on SD-OCT.
Epiretinal membrane (ERM) is a pathological condition characterized by the formation of a non-vascularized fibrocellular membrane on the inner retinal surface, leading to retinal traction, macular edema, and visual impairment. Optical coherence tomography (OCT) is the primary imaging modality for diagnosing macular …
About these results
- Corpus
- 10,000 abstracts released in PubMed Central from 2026-01-01 to 2026-01-14
- Licences
- 9,963 CC BY, 37 CC0
- Preprints
- 166, labelled
- Query encoder
- ncbi/MedCPT-Query-Encoder at d83a36cc
- Article encoder
- ncbi/MedCPT-Article-Encoder at d05a736d
- Embeddings computed
- 2026-11-03, at commit a619493
- Documents updated
- 2026-11-03, at commit 6b9c71e: added authors and publication types; titles, abstracts and order unchanged, so the embeddings were kept